Purified Anti-Human CD45RA Antibody[HI100]
![Purified Anti-Human CD45RA Antibody[HI100]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性: FCM
- 亚型: Mouse IgG2b, κ
- 宿主: Mouse
Alternate Names | CD45, L-CA, Ly-5, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200 |
Clone No | |
Isotype | Mouse IgG2b, κ |
Leadtime |
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Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
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Background |
CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.
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Immunogen | Recombinant Human CD45RA protein |
Abbre | CD45RA |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Purification Method | >98%, Protein A/G purified |
Applications | |
Research Areas | Cell Biology;Immunology;Inhibitory Molecules;Neuroscience;Neuroscience Cell Markers |
Concentration | ≥ 1 mg/mL |
Conjugation | Unconjugated |
Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12个月 |
Shipping |
Ice bag |
Human peripheral blood lymphocytes were stained with 0.2 μg Purified Anti-Human CD45RA Antibody[HI100] (Right) and 0.2 μg Mouse IgG2b, κ Isotype Control (Left), followed by Alexa Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
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EMF treatment delays mesenchymal stem cells senescence during long-term in vitro expansion by modulating autophagy
IF: 4.600Journal: Frontiers in Cell and Developmental Biology (2024)Reactivity:Rat
E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |