Purified Anti-Human CD8a Antibody[HIT8a]
![Purified Anti-Human CD8a Antibody[HIT8a]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性: FCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Alternate Names | CD8, Leu-2, Ly-2, CD8, CD8 antigen alpha po, CD8 antigen alpha polypeptide, CD8A, Leu, Leu2, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu, T-lymphocyte differentiation antigen T8/Leu-2, T8, alpha polypeptide (p32), p32 |
Clone No | |
Isotype | Mouse IgG1, κ |
Leadtime |
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Background |
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
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Abbre | CD8a |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Applications | |
Research Areas | Immunology |
Concentration | ≥ 1 mg/mL |
Conjugation | Unconjugated |
Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12个月 |
Shipping |
Ice bag |
Human peripheral blood lymphocytes cell were stained with 0.2 μg Purified Anti-Human CD8a Antibody[HIT8a] (Right) and 0.2 μg Mouse IgG1, κ Isotype Control (Left), followed by Alexa Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |