Purified Anti-Mouse IL-17A Antibody[17F3]
![Purified Anti-Mouse IL-17A Antibody[17F3]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性： ICFCM
- 亚型： Mouse IgG1, κ
- 宿主： Mouse
| Alternate Names | Ctla9, Il17a, Interleukin-17A |
| Clone No | |
| Isotype | Mouse IgG1, κ |
| Leadtime |
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| Background |
The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A in vivo.
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| Abbre | IL-17A |
| Swissprot | |
| Host | Mouse |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Applications | |
| Research Areas | Cell Biology;Immunology;Neuroinflammation;Neuroscience |
| Concentration | ≥ 1 mg/mL |
| Conjugation | Unconjugated |
| Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12个月 |
| Shipping |
Ice bag |
HEK293T cells transfected with pcDNA3.1 plasmid encoding Mouse IL-17A gene were stained with 0.2 μg Purified Anti-Mouse IL-17A Antibody[17F3] (Right) and 0.2 μg Mouse IgG1, κ Isotype Control (Left), followed by Alexa Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
| E-CK-A091 | Cell Stimulation and Protein Transport Inhibitor Kit | 500Assays , 200Assays , 100Assays , 50Assays |
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
| E-CK-A109 | Intracellular Fixation/Permeabilization Buffer Kit | 500Assays , 100Assays , 50Assays |
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