Recombinant Human MR-ProADM protein(GST Tag)
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- 表达系统： E.coli
- 蛋白编码： P35318
| 别称 |
AM;PAMP;ProAM N-terminal 20 peptide;ProAM-N20
|
| 表达系统 |
E.coli
|
| 序列 |
Glu45-Val92
|
| 蛋白编码 |
P35318
|
| 种属 |
Human
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| 计算分子量 |
31.3 kDa
|
| 表观分子量 |
32 kDa
|
| 标签 |
N-GST
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| 生物活性 |
Not validated for activity
|
| 纯度 |
> 85% as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
|
| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
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实验操作视频
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