Recombinant Mouse ACVRL1 Protein(His Tag)
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- 表达系统： Mammalian
- 蛋白编码： Q61288
| 别称 |
Activin A receptor;Activin A receptor type II like 1;Activin A receptor;type II like kinase 1;Activin receptor like kinase 1;Activin receptor-like kinase 1;ACVL1;ACVRL1;ACVRLK1;ALK-1;ALK1;HHT;HHT2;ORW2;Osler Rendu Weber syndrome 2;Serine/threonine protein kinase receptor R3;Serine/threonine-protein kinase receptor R3;SKR3;TGF B superfamily receptor type I;TGF-B superfamily receptor type I;TSR-I;TSR1
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| 表达系统 |
Mammalian
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| 序列 |
Asp23-Pro119
|
| 蛋白编码 |
Q61288
|
| 种属 |
Mouse
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| 计算分子量 |
10.5 kDa
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| 表观分子量 |
20-30 kDa
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| 标签 |
C-His
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 90% as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with an other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine-and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with an other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with an hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
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实验操作视频
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