Serpin E1/PAI-1 Polyclonal Antibody(Capture/Detector)

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- 宿主: Rabbit
- 反应性: Rat
- 应用性: WB;ELISA Capture/Detector
Verified Samples |
Verified Samples in WB: Rat placenta Verified Samples in ELISA: Recombinant Rat Serpin E1/PAI-1 protein, Rat serum, Rat plasma |
Dilution | WB 1:500-1:1000, ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Immunogen | Recombinant Rat Serpin E1/PAI-1 protein expressed by Mammalian |
Abbre | Serpin E1/PAI-1 |
Synonyms | PLasminogen activator inhibitor 1, PAI-1, EndotheLiaL pLasminogen activator inhibitor, Serpin E1, SERPINE1, PLANH1 |
Swissprot | |
Calculated MW | 45 kDa |
Observed MW | 47 kDa |
Concentration | 1 mg/mL |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Purification Method | Antigen Affinity Purification |
Conjugation | Unconjugated |
Background | Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PlAT) and urokinase-type plasminogen activator (PlAU). As PlAT inhibitor,it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PlAU inhibitor,it is involved in the regulation of cell adhesion and spreading.Acts as a regulator of cell migration,independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells,and regulates odontoblast differentiation and dentin formation during odontogenesis. |
PDMR100067 | Recombinant Rat Serpin E1/PAI-1 Protein(His Tag) | 100 μg , 20 μg |