TIM-1/KIM-1/HAVCR Polyclonal Antibody(Capture/Detector)

Price:
- 宿主: Rabbit
- 反应性: pig
- 应用性: ELISA Capture/Detector
Verified Samples |
Verified Samples in ELISA: Recombinant Pig TIM-1/KIM-1/HAVCR protein, Pig serum, Pig plasma |
Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Immunogen | Recombinant Pig TIM-1/KIM-1/HAVCR protein expressed by Mammalian |
Abbre | TIM-1/KIM-1/HAVCR |
Synonyms | HAVCR1, HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1, |
Swissprot | |
Concentration | 1 mg/mL |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Purification Method | Antigen Affinity Purification |
Research Areas | Cancer, Immunology, Microbiology |
Conjugation | Unconjugated |
Background | HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest levels in the kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy, and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling. |