uPAR Monoclonal Antibody(Capture)

Price:
- 宿主: Rat
- 反应性: Human
- 应用性: ELISA Capture
Verified Samples |
Verified Samples in ELISA: Recombinant Human uPAR protein, Human serum, Human plasma |
Dilution | ELISA Capture 2-8 μg/mL |
Clonality | Monoclonal |
Isotype | Rat IgG1 |
Immunogen | Recombinant Human uPAR protein expressed by Mammalian |
Abbre | uPAR |
Synonyms | CD87, U-PAR, URKR, |
Swissprot | |
Concentration | 1 mg/mL |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Purification Method | Protein A/G Purification |
Research Areas | Cancer, Cardiovascular, Immunology |
Clone No. | 5E5 |
Conjugation | Unconjugated |
Background | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |
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