VCAM-1/CD106 Polyclonal Antibody(Capture/Detector)
Price:
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC;ELISA Capture/Detector
| Verified Samples |
Verified Samples in WB: Mouse spleen, Rat kidney, Rat spleen Verified Samples in IHC: Human Kidney cancer Verified Samples in ELISA: Recombinant Rat VCAM-1/CD106 protein, Rat serum, Rat plasma |
| Dilution | WB 1:500-1:1000, IHC 1:1000-1:2000, ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | Recombinant Rat VCAM-1/CD106 protein expressed by Mammalian |
| Abbre | VCAM-1/CD106 |
| Synonyms | CD106, Vcam1, Vcam-1, V-CAM 1, VascuLar ceLL adhesion protein 1, SoLubLe VascuLar CeLL Adhesion MoLecuLe-1 |
| Swissprot | |
| Calculated MW | 81 kDa |
| Observed MW | 75-100 kDa |
| Concentration | 1 mg/mL |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Background | Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses,binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation. |
