AF/LE Purified Anti-Mouse CD8a Antibody[53-6.7]
![AF/LE Purified Anti-Mouse CD8a Antibody[53-6.7]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性： FCM
- 亚型： Rat IgG2a, κ
- 宿主： Rat
| Alternate Names | CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2 |
| Clone No | |
| Isotype | Rat IgG2a, κ |
| Leadtime |
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| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
| Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
|
| Background |
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
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| Immunogen | Recombinant Mouse CD8a protein |
| Abbre | CD8a |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Applications | |
| Concentration | ≥ 1 mg/mL |
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12个月 |
| Shipping |
Ice bag |
C57/BL6 Mouse splenocytes were stained with 0.2 μg AF/LE Purified Anti-Mouse CD8a Antibody[53-6.7] (Right) and 0.2 μg Rat IgG2a, κ Isotype Control (Left), followed by Alexa Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody, then anti-Mouse CD4 FITC-conjugated Monoclonal Antibody.
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