BCL2 Monoclonal Antibody
Price:
- 宿主： Mouse
- 反应性： Human
- 应用性： WB
| Verified Samples |
Verified Samples in WB: Hela Verified Samples in IHC: Human tonsil |
| Dilution | WB 1:1000-2000 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Synthetic Peptide |
| Abbre | Bcl-2 |
| Synonyms | 2, AW986256, Apoptosis regulator Bcl 2, Apoptosis regulator Bcl-2, Apoptosis regulator Bcl2, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, B-cell, BCL2, Bcl-2, Bcl2, C430015F12Rik, D630044D05Rik, D830018M01Rik, Leukemia/lymphoma, Oncogene B-cell leukemia 2, PPP1R50 |
| Swissprot | |
| Calculated MW | 26 kDa |
| Observed MW | 26 kDa |
| Cellular Localization | Mitochondrion outer membrane. Nucleus membrane. Endoplasmic reticulum membrane. |
| Tissue Specificity | Expressed in a variety of tissues |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction |
| Clone No. | 1B3 |
| Conjugation | Unconjugated |
| Background | Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). |
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The Antioxidant and Proapoptotic Effects of Sternbergia clusiana Bulb Ethanolic Extract on Triple-Negative and Estrogen-Dependent Breast Cancer Cells In Vitro
IF: 4.500 -
Boric Acid (Boron) Attenuates AOM-Induced Colorectal Cancer in Rats by Augmentation of Apoptotic and Antioxidant Mechanisms
IF: 3.900Journal： BIOLOGICAL TRACE ELEMENT RESEARCH (2023)PMID：37770673Reactivity：RatSample Type：colon tissues -
L-carnitine reverses methotrexate-induced nephrotoxicity in experimental rat model: Insight on SIRT1/PGC-1α/Nrf2/HO-1 axis
IF: 3.300Journal： JOURNAL OF APPLIED TOXICOLOGY (2023)DOI：10.1002/jat.4503PMID：37312617Reactivity：RatSample Type：renal -
Achyranthes bidentate extracts protect the IL-1β-induced osteoarthritis of SW1353 chondrocytes
IF: 2.800 -
Infliximab Ameliorates Methotrexate-Induced Nephrotoxicity in Experimental Rat Model: Impact on Oxidative Stress, Mitochondrial Biogenesis, Apoptotic and Autophagic Machineries
IF: 2.600Journal： CELL BIOCHEMISTRY AND BIOPHYSICS (2023)PMID：37656380Reactivity：RatSample Type：renal tissue -
Pinostrobin attenuates azoxymethane-induced colorectal cytotoxicity in rats through augmentation of apoptotic Bax/Bcl-2 proteins and antioxidants
IF: 2.300 -
Tilianin Reduces Apoptosis via the ERK/EGR1/BCL2L1 Pathway in Ischemia/Reperfusion-Induced Acute Kidney Injury Mice
IF: 5.988 -
Leech therapy (Hirudo medicinalis) attenuates testicular damages induced by testicular ischemia/reperfusion in an animal model
IF: 2.741 -
Gastroprotective effect of gallic acid against ethanol-induced gastric ulcer in rats: Involvement of the Nrf2/HO-1 signaling and anti-apoptosis role
IF: 4.545 -
The anti-cancer effect of flaxseed lignan derivatives on different acute myeloid leukemia cancer cells
IF: 4.545Journal： BIOMEDICINE & PHARMACOTHERAPY (2020)PMID：33080470Reactivity：HumanSample Type：Cell sample
| E-AB-1001 | Goat Anti-Mouse IgG(H+L)(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1024 | Goat Anti-Mouse IgG(H+L)(Biotin conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1196 | HRP-Goat Anti-Mouse IgG(H+L) preadsorbed | 500 μL , 120 μL , 1 mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 50 mL , 18 mL , 6 mL , 3 mL |
| E-IR-R220 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50 Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |
