Caspase 3/7 Activity Assay Kit(Colorimetric Method)

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中文名称：Caspase 3/7活性检测试剂盒(分光光度法)

货号：E-CK-A383
文献（84）
说明书

说明书

Caspase 3/7 Activity Assay Kit(Colorimetric Method)

Price: ¥1800.00 ¥1000.00 ¥500.00

Size:

100 Assays 50 Assays 20 Assays

应用： 细胞凋亡-Caspase

细胞凋亡检测试剂盒全线5折

2025-08-19 ~ 2025-09-30

检测原理	Caspase 3也称CPP32、Yama或apopain，属于Caspase家族的CED-3亚家族(CED-3 subfamily)，是细胞凋亡过程中的一个关键酶，也是哺乳动物细胞中研究最多的一个caspase。Caspase 3在正常状态下以酶原的形式存在于胞浆中，没有活性；在细胞发生凋亡阶段，Caspase 3被激活，活化的caspase 3由两个大亚基和两个小亚基组成，裂解相应的胞浆胞核底物，最终导致细胞凋亡。本caspase 3/7活性检测试剂盒是基于caspase 3/7可以催化底物Ac-DEVD-pNA产生黄色的pNA(p-nitroaniline)，pNA在405nm附近有强吸收，从而可以通过测定吸光度来检测caspase 3/7的活性。
检测方法	比色法
样本类型	细胞;组织
检测时间	4-6 hours
检测仪器	分光光度计;酶标仪
自备试剂	PBS(E-BC-R187)，Bradford蛋白测定试剂盒(E-BC-K168-S或E-BC-K168-M)
保存温度	该产品可在-20°C避光条件下保存12个月。
有效期	12个月
运输条件	冰袋

pNA Standard Curve

Newcastle disease virus infection induces parthanatos in tumor cells via calcium waves

IF: 5.5

Journal： PLoS Pathogens (2024)

DOI：10.1371/journal.ppat.1012737

Reactivity：Human
Intraperitoneal Injection of the Porphyromonas gingivalis Outer Membrane Vesicle (OMV) Stimulated Expressions of Neuroinflammatory Markers and Histopathological Changes in the Brains of Adult Zebrafish

IF: 4.9

Journal： INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2024)

DOI：10.3390/ijms252011025

Reactivity：Zebrafish

Sample Type：brain tissue
Serum pharmacochemistry combined with network pharmacology reveals the hepatotoxicity mechanism of Alangium chinense (Lour.) Harms

IF: 4.8

Journal： JOURNAL OF ETHNOPHARMACOLOGY (2024)

DOI：10.1016/j.jep.2024.119312

Reactivity：Rat

Sample Type：liver tissue
Cytotoxicity effects and differentiation potential of ormocer-based and nanohybrid composite resins on human dental pulp stem cells\

IF: 4.6

Journal： DENTAL MATERIALS (2024)

DOI：10.1016/j.dental.2024.05.011

Reactivity：Human
Tocilizumab unfolds colo-protective and immunomodulatory effect in experimentally induced ulcerative colitis via mitigating autophagy and ER stress signaling

IF: 4.6

Journal： INFLAMMOPHARMACOLOGY (2024)

DOI：10.1007/s10787-024-01527-7

Reactivity：Rat

Sample Type：colon tissue
Anti-cancer activity of Brucine loaded Cu(OH)2/ZnO Nanoparticles Against Chronic Myeloid Leukemia Cell Line (K562) via apoptotic signaling Pathway

IF: 4.5

Journal： JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2024)

DOI：10.1016/j.jddst.2024.106159

Reactivity：Human
AT11-guided liposomes for oral cancer cells: From characterization towards in vitro evaluation

IF: 4.5

Journal： JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2024)

DOI：10.1016/j.jddst.2024.106214
Novel 1,2,4-triazole-maleamic acid derivatives: synthesis and evaluation as anticancer agents with carbonic anhydrase inhibitory activity

IF: 4.0

Journal： JOURNAL OF MOLECULAR STRUCTURE (2024)

DOI：10.1016/j.molstruc.2024.138680
Bifidobacterium longum JBLC-141 alleviates hypobaric hypoxia-induced intestinal barrier damage by attenuating inflammatory responses and oxidative stress

IF: 4.0

Journal： Frontiers in Microbiology (2024)

DOI：10.3389/fmicb.2024.1501999

Reactivity：Rat

Sample Type：colonic tissue
Human Melanoma and Glioblastoma Cells Express Cathepsins Supporting Reovirus Moscow Strain Infection

IF: 3.8

Journal： Viruses-Basel (2024)

DOI：10.3390/v16121944

Reactivity：Human

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