Caspase 3/7 Activity Assay Kit(Colorimetric Method)

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中文名称：Caspase 3/7活性检测试剂盒(分光光度法)

货号：E-CK-A383
文献（84）
说明书

说明书

Caspase 3/7 Activity Assay Kit(Colorimetric Method)

Price: ¥1800.00 ¥1000.00 ¥500.00

Size:

100 Assays 50 Assays 20 Assays

应用： 细胞凋亡-Caspase

细胞凋亡检测试剂盒全线5折

2025-08-19 ~ 2025-09-30

检测原理	Caspase 3也称CPP32、Yama或apopain，属于Caspase家族的CED-3亚家族(CED-3 subfamily)，是细胞凋亡过程中的一个关键酶，也是哺乳动物细胞中研究最多的一个caspase。Caspase 3在正常状态下以酶原的形式存在于胞浆中，没有活性；在细胞发生凋亡阶段，Caspase 3被激活，活化的caspase 3由两个大亚基和两个小亚基组成，裂解相应的胞浆胞核底物，最终导致细胞凋亡。本caspase 3/7活性检测试剂盒是基于caspase 3/7可以催化底物Ac-DEVD-pNA产生黄色的pNA(p-nitroaniline)，pNA在405nm附近有强吸收，从而可以通过测定吸光度来检测caspase 3/7的活性。
检测方法	比色法
样本类型	细胞;组织
检测时间	4-6 hours
检测仪器	分光光度计;酶标仪
自备试剂	PBS(E-BC-R187)，Bradford蛋白测定试剂盒(E-BC-K168-S或E-BC-K168-M)
保存温度	该产品可在-20°C避光条件下保存12个月。
有效期	12个月
运输条件	冰袋

pNA Standard Curve

Thymoquinone Induces Nrf2 Mediated Adaptive Homeostasis: Implication for Mercuric Chloride-Induced Nephrotoxicity

IF: 4.132

Journal： ACS Omega (2022)

DOI：10.1021/acsomega.2c00028

PMID：35252727
Green-Based Approach to Synthesize Silver Nanoparticles Using the Fungal Endophyte Penicillium oxalicum and Their Antimicrobial, Antioxidant, and In Vitro Anticancer Potential

IF: 4.132

Journal： ACS Omega (2022)

DOI：10.1021/acsomega.2c05605
Balancing between apoptosis and survival biomarkers in the patients with tuberculous meningitis

IF: 3.926

Journal： CYTOKINE (2022)

DOI：10.1016/j.cyto.2022.155960

PMID：35820324

Reactivity：Human

Sample Type：serum , CSF
Calcium?dependent activation of PHEX, MEPE and DMP1 in osteocytes

IF: 3.423

Journal： Molecular Medicine Reports (2022)

DOI：10.3892/mmr.2022.12876

PMID：36281920
Verbascoside potentiates the effect of tyrosine kinase inhibitors on the induction of apoptosis and oxidative stress via the Abl-mediated MAPK signalling pathway in chronic myeloid leukaemia

IF: 2.751

Journal： Experimental and Therapeutic Medicine (2022)

DOI：10.3892/etm.2022.11441

PMID：35837042
Silencing CircEIF3I/miR-526b-5p Axis Epigenetically Targets HGF/c-Met Signal to Hinder the Malignant Growth, Metastasis and Angiogenesis of Hepatocellular Carcinoma

IF: 2.220

Journal： BIOCHEMICAL GENETICS (2022)

DOI：10.1007/s10528-022-10239-y

PMID：35723810
Trimetazidine Modulates Mitochondrial Redox Status and Disrupted Glutamate Homeostasis in a Rat Model of Epilepsy

IF: 5.811

Journal： Frontiers in Pharmacology (2021)

DOI：10.3389/fphar.2021.735165

PMID：34690772
Vitamin D and rosuvastatin obliterate peripheral neuropathy in a type-2 diabetes model through modulating Notch1, Wnt-10α, TGF-β and NRF-1 crosstalk

IF: 5.037

Journal： LIFE SCIENCES (2021)

DOI：10.1016/j.lfs.2021.119697

Reactivity：Rat

Sample Type：sciatic nerve
Ameliorative Potential of Hydroethanolic Leaf Extract of Parquetina nigrescens on d-Galactose-Induced Testicular Injury

IF: 4.412

Journal： MOLECULES (2021)

DOI：10.3390/molecules26113424

PMID：34198754

Reactivity：Rat

Sample Type：testicular
Neuroprotective effects of indole-3-carbinol on the rotenone rat model of Parkinson's disease: Impact of the SIRT1-AMPK signaling pathway

IF: 4.219

Journal： TOXICOLOGY AND APPLIED PHARMACOLOGY (2021)

DOI：10.1016/j.taap.2021.115853

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