Catenin beta Monoclonal Antibody
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Price:
Size:
120 μL
60 μL
- 宿主： Mouse
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB: Mouse lung, Mouse kidney, Rat kidney Verified Samples in IHC: Human colon, Mouse stomach, Rat stomach |
| Dilution | WB 1:500-1:1000, IHC 1:100-1:500 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein corresponding to Mouse β-catenin |
| Abbre | Catenin beta |
| Synonyms | 88kDa, Beta catenin, Beta-catenin, CATNB, CHBCAT, CTNB1, CTNNB, CTNNB1, Cadherin associated protein, Catenin (cadherin associated protein), Catenin beta 1, Catenin beta-1, DKFZp686D02253, FLJ25606, FLJ37923, OTTHUMP00000162082, OTTHUMP0000016522, OTTHUMP00000165222, beta 1 |
| Swissprot | |
| Calculated MW | 92 kDa |
| Observed MW | 92 kDa |
| Concentration | 420 μg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Neuroscience, Signal Transduction, Stem Cells |
| Clone No. | 4A3H3 |
| Conjugation | Unconjugated |
| Background | CTNNB1,also known as β-Catenin,is an evolutionarily conserved,multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs,CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. . |
Western Blot analysis of various samples using Catenin beta Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded Human colon using Catenin beta Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded mouse stomach using Catenin beta Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded Rat stomach using Catenin beta Monoclonal Antibody at dilution of 1:200.
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