CK-7 Monoclonal Antibody

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Price:
Size:
120 μL
60 μL
- 宿主: Mouse
- 反应性: Human;Mouse;Rat
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB: HepG2, A549, A431, Mouse lung, Mouse kidney, Mouse colon, Rat lung, Rat kidney, Rat colon Verified Samples in IHC: Human stomach cancer, Mouse stomach cancer, Rat stomach cancer |
Dilution | WB 1:500-1:2000, IHC 1:100-1:500 |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | Recombinant protein corresponding to Mouse Cytokeratin 7 |
Abbre | CK-7 |
Synonyms | 55K type II cytoskeletal, CK 7, CK-7, CK7, Cytokeratin 7, Cytokeratin-7, D15Wsu77e, K2C7, K7, Kerat, Keratin, Keratin 7, Keratin type II cytoskeletal 7, simple epithelial, simple epithelial type I, type II, type II cytoskeletal 7 |
Swissprot | |
Calculated MW | 51 kDa |
Observed MW | 51 kDa |
Concentration | 2.8 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Signal Transduction |
Clone No. | 7D8G8 |
Conjugation | Unconjugated |
Background | Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells,which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins,including K9–K23,and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins,including K1–K8,and the hair keratins,Hb1–Hb6. KRT7,also named as cytokeratin 7,is one member of type II basic cytokeratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels,and their neoplasms. KRT7 is marker of epithelial tissues,but not present in carcinomas of stratified squamous cell origin.This antibody is specifically against KRT7. |
Western Blot analysis of various samples using CK-7 Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded human stomach cancer using CK-7 Monoclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse stomach cancer using CK-7 Monoclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded Rat stomach cancer using CK-7 Monoclonal Antibody at dilution of 1:300.
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Gut microbiota modulate CD8+ T cell immunity in gastric cancer through Butyrate/GPR109A/HOPX
IF: 12.200
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