E-Cadherin Monoclonal Antibody

Price:
Size:
120 μL
60 μL
- 宿主: Mouse
- 反应性: Mouse;Rat
- 应用性: IHC
Verified Samples |
Verified Samples in IHC: Mouse liver, Rat colon, Rat pancreas |
Dilution | IHC 1:200-1:800 |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | Recombinant protein corresponding to MouseE-cadherin |
Abbre | E-Cadherin |
Synonyms | Arc 1, CADH1, CAM 120/80, CD 324, CD324, CD324 antigen, CDHE, Cadherin 1, Cadherin1, E-Cad/CTF3, E-cadherin, ECAD, Epithelial cadherin, LCAM, Liver cell adhesion molecule, UVO, Uvomorulin, cadherin 1 type 1 E-cadherin, cdh1, epithelial calcium dependant adhesion protein |
Swissprot | |
Concentration | 1.6 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Developmental Biology, Signal Transduction |
Clone No. | EC125D |
Conjugation | Unconjugated |
Background | This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. |
Immunohistochemistry analysis of paraffin-embedded mouse liver using E-Cadherin Monoclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat colon using E-Cadherin Monoclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat pancreas using E-Cadherin Monoclonal Antibody at dilution of 1:300.
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E-AB-1024 | Goat Anti-Mouse IgG(H+L)(Biotin conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
E-AB-1196 | HRP-Goat Anti-Mouse IgG(H+L) preadsorbed | 500 μL , 120 μL , 1 mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 50 mL , 18 mL , 6 mL , 3 mL |
E-IR-R220 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50 Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |