Histone H3 Monoclonal Antibody

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- 宿主: Mouse
- 反应性: Zebrafish
- 应用性: WB
Verified Samples |
Verified Samples in WB: Zebrafish skeletal muscle |
Dilution | WB 1:1000-3000 |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | Synthetic Peptide |
Abbre | Histone H3 |
Synonyms | H3FA, H3FB, H3FC, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, Histone H3.1, Histone H3/, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f |
Swissprot | |
Calculated MW | 15 kDa |
Observed MW | 15 kDa |
Cellular Localization | Extracellular region or secreted, extracellular exosome, extracellular region, Nucleus, nuclear chromosome, nuclear chromosome, telomeric region, nuclear nucleosome, nucleoplasm, nucleus, Other locations: nucleosome, protein complex. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
Purification Method | Protein A purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling |
Clone No. | 3C5 |
Conjugation | Unconjugated |
Background | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
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