Lipid Peroxide (LPO) Fluorometric Assay Kit

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中文名称：脂质过氧化物（LPO）荧光法测试盒

货号：E-BC-F003
文献（15）
说明书

说明书

Lipid Peroxide (LPO) Fluorometric Assay Kit

Price: ¥3288.00

Size:

96 T

样本类型： 细胞
检测仪器及波长： 荧光酶标仪（Ex/Em=500 nm/540 nm）、流式细胞仪（FITC）、荧光显微镜（FITC或GFP）
研究领域： 铁死亡

说明书或网站上未涉及的样本类型请先跟技术支持沟通，可进行售前验证

根据需测样本数，试剂盒测样本孔数和单个样本测量孔数来计算所需生化试剂盒数量，请点击按钮计算

生化试剂盒数量计算器x

需测样本数：

单个样本测量孔数：

试剂盒测样本孔数：

计算

所需盒子量：

检测原理	脂质过氧化物（LPO）是不饱和脂肪酸经过活性氧的作用所生成的物质。生成的LPO会继续氧化脂质体，从而在连锁反应中不断积累LPO。过量的LPO会分解成Acrolein, Malondialdehyde (MDA)，4-hydroxy-2-nonenal (4-NHE)等具有高活性的醛类物质，对细胞产生毒性进而造成细胞死亡。本试剂盒提供一种可以检测LPO形成的荧光探针C11-BODIPY 581/591。这种荧光探针可以与脂质过氧化途径中的脂质自由基等发生反应，从而起到检测细胞内脂质过氧化水平的作用。该荧光探针在正常情况下通过光激发发出红色荧光，随着脂质过氧化的过程荧光会从红色变为绿色。通过绿色荧光强度的增强，可以高灵敏度的检测LPO的形成。
指标简称	LPO
检测仪器及波长	荧光酶标仪（Ex/Em=500 nm/540 nm）、流式细胞仪（FITC）、荧光显微镜（FITC或GFP）
保存条件	该产品可在-20°C避光条件下保存3个月。
有效期	3个月

Multimodal enhancement of ferroptosis for synergistic cascade colorectal cancer therapy

IF: 13.300

Journal： CHEMICAL ENGINEERING JOURNAL (2024)

DOI：10.1016/j.cej.2024.155048

Reactivity：Mouse
Blocking METTL3-mediated lncRNA FENDRR silence reverses cisplatin resistance of lung adenocarcinoma through activating TFRC-mediated ferroptosis pathway

IF: 2.900

Journal： JOURNAL OF MOLECULAR HISTOLOGY (2024)

DOI：10.1007/s10735-024-10276-4

Reactivity：Human
Impact of heavy metals, oxidative stress, expression of VHL, and antioxidant genes in the pathogenesis of renal cell carcinoma

IF: 2.400

Journal： UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2024)

DOI：10.1016/j.urolonc.2024.08.015

Reactivity：Human

Sample Type：Serum
Targeting the Na+/K+ ATPase DR-region with DR-Ab improves doxorubicin-induced cardiotoxicity

IF: 7.400

Journal： FREE RADICAL BIOLOGY AND MEDICINE (2023)

DOI：10.1016/j.freeradbiomed.2023.04.008

PMID：37100355

Reactivity：Mouse

Sample Type：heart tissue
Low intensity pulsed ultrasound ameliorates Adriamycin-induced chronic renal injury by inhibiting ferroptosis

IF: 3.800

Journal： REDOX REPORT (2023)

DOI：10.1080/13510002.2023.2251237

PMID：37652897

Reactivity：Rat

Sample Type：renal cortex
Electroacupuncture ameliorates chronic unpredictable mild stress-induced depression-like behavior and cognitive impairment through suppressing oxidative stress and neuroinflammation in rats

IF: 3.800

Journal： BRAIN RESEARCH BULLETIN (2023)

DOI：10.1016/j.brainresbull.2023.110838

PMID：38123022

Reactivity：Rat

Sample Type：hippocampus tissue
Bone marrow mesenchymal stem cells inhibit ferroptosis via regulating the Nrf2-keap1/p53 pathway to ameliorate chronic kidney disease injury in the rats

IF: 2.800

Journal： JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2023)

DOI：10.1080/10799893.2023.2185083

PMID：36883687

Reactivity：Rat

Sample Type：kidney
Myostatin/HIF2α-Mediated Ferroptosis is Involved in Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease

IF: 2.893

Journal： International Journal of Chronic Obstructive Pulmonary Disease (2022)

DOI：10.2147/COPD.S377226

PMID：36185172

Reactivity：Mouse

Sample Type：skeletal muscle
The Anti-Inflammatory Effect of a Combination of Five Compounds From Five Chinese Herbal Medicines Used in the Treatment of COPD

IF: 5.811

Journal： Frontiers in Pharmacology (2021)

DOI：10.3389/fphar.2021.709702

PMID：34776947

Reactivity：Rat

Sample Type：serum
Antioxidant Activity Derived from Marine Green-Lipped Mussel Perna canaliculus Extracts in Mice

IF: 3.411

Journal： Biomed Research International (2021)

DOI：10.1155/2021/1622270

PMID：34409099

Reactivity：Mouse

Sample Type：liver, kidney, cardiac

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