ABCB5 Monoclonal Antibody

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- 宿主: Mouse
- 反应性: Human
- 应用性: WB;IHC-p;IF
Verified Samples |
Verified Samples in WB: Hela, 293T Verified Samples in IHC: Human breast cancer Verified Samples in IF: Human liver cancer |
Dilution | WB 1:500-1:3000, IHC 1:50-1:300, IF 1:100-1:300 |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | Synthetic Peptide |
Abbre | ABCB5 |
Synonyms | ABCB 5, ABCB5, ABCB5 P-gp, ABCB5alpha, ABCB5beta, ATP binding cassette protein, ATP binding cassette sub family B (MDR/TAP) member 5, ATP binding cassette sub family B member 5, ATP-binding cassette sub-family B member 5, EST422562, P glycoprotein ABCB5, P-gly |
Swissprot | |
Calculated MW | 90 kDa |
Observed MW | 90 kDa |
Cellular Localization | Cell membrane. |
Tissue Specificity | Expressed by CD133-expressing progenitor cells among epidermal melanocytes (at protein level). Widely expressed with specific expression in pigment cells. Also expressed in several malignant tissues. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
Purification Method | Protein A purification |
Research Areas | Cancer, Metabolism, Signal Transduction |
Clone No. | 7L3 |
Conjugation | Unconjugated |
Background | ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules. |