AFP Monoclonal Antibody

Price:
- 宿主: Mouse
- 反应性: Human
- 应用性: WB;IHC-p;IF
Verified Samples |
Verified Samples in WB: HepG2 Verified Samples in IHC: Human breast cancer Verified Samples in IF: Human breast cancer |
Dilution | WB 1:500-1:3000, IHC 1:50-1:300, IF 1:100-1:300 |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | Synthetic Peptide |
Abbre | AFP alpha 1 Fetoprotein |
Synonyms | AFPD, Afp, Alpha fetoglobulin, Alpha fetoprotein, Alpha fetoprotein precursor, Alpha-1-fetoprotein, Alpha-fetoglobulin, Alpha-fetoprotein, FETA, HPAFP, Hereditary persistence of, Hereditary persistence of alpha fetoprotein, alpha-fetoprotein, included |
Swissprot | |
Observed MW | 70 kDa |
Cellular Localization | Secreted. |
Tissue Specificity | Plasma Synthesized by the fetal liver and yolk sac |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
Purification Method | Protein A purification |
Research Areas | Cancer, Cardiovascular, Developmental Biology |
Clone No. | 2L6 |
Conjugation | Unconjugated |
Background | This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |