BAX Polyclonal Antibody（D-AB-10386L）|-Elabscience伊莱瑞特【官网】

BAX Polyclonal Antibody

一键复制产品信息

货号：D-AB-10386L
文献（14）
说明书

说明书

Price: ¥2100.00 ¥800.00

Size:

100 μL 25 μL

宿主： Rabbit
反应性： Human;Mouse;Rat
应用性： WB

Verified Samples	Verified Samples in WB: MCF-7, A549, HepG2, SH-SY5Y, C2C12, NIH-3T3, Raw264.7, C6
Dilution	WB 1:500-1:1000
Clonality	Polyclonal
Isotype	IgG
Immunogen	Recombinant Human BAX Protein expressed by E.coli
Abbre	BAX
Synonyms	Apoptosis regulator BAX, BAX, BCL2L4, Bcl-2-like protein 4 (Bcl2-L-4)
Swissprot	Q07812
Calculated MW	4 kDa/12 kDa/15 kDa/18 kDa/19 kDa/21 kDa/24 kDa
Observed MW	20 kDa
Concentration	1 mg/mL
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer	PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Purification Method	Antigen Affinity Purification
Research Areas	Cancer, Cell Biology, Metabolism
Conjugation	Unconjugated
Background	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2,and functions as an apoptotic activator. This protein is reported to interact with,and increase the opening of,the mitochondrial voltage-dependent anion channel (VDAC),which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants,which encode different isoforms,have been reported for this gene.

Western blot with BAX Polyclonal antibody at dilution of 1:1000.lane 1:MCF-7 whole cell lysate,lane 2:A549 whole cell lysate,lane 3:HepG2 whole cell lysate,lane 4:SH-SY5Y whole cell lysate,lane 5:C2C12 whole cell lysate,lane 6:NIH-3T3 whole cell lysate,lane 7:Raw264.7 whole cell lysate,lane 8:C6 whole cell lysate

Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro

IF: 6.126

Journal： Cancers (2020)

DOI：10.3390/cancers12020435

PMID：32069824

Reactivity：Human

Sample Type：Cell sample
Erxian decoction, a famous Chinese medicine formula, antagonizes corticosterone-induced injury in PC12 cells, and improves depression-like behaviours in mice

IF: 2.971

Journal： PHARMACEUTICAL BIOLOGY (2020)

DOI：10.1080/13880209.2020.1765812

PMID：32476554

Reactivity：Mouse

Sample Type：Tissue homogenate
The selective anti-proliferative and pro-apoptotic effect of A. cherimola on MDA-MB-231 breast cancer cell line

Journal： BMC Complementary Medicine and Therapies (2020)

DOI：10.1186/s12906-020-03120-1

PMID：33187495

Reactivity：Human

Sample Type：Cell sample
A novel peptide, 9R-P201, strongly inhibits the viability, proliferation and migration of liver cancer HepG2 cells and induces apoptosis by down-regulation of FoxM1 expression

IF: 2.730

Journal： EUROPEAN JOURNAL OF PHARMACOLOGY (2016)

DOI：10.1016/j.ejphar.2016.12.029

PMID：28012972

Reactivity：Human

Sample Type：Cell lysate

E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500 μL , 120 μL , 1 mL
E-IR-R304A	Western Blot Detection Kit	50 Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50 Assays