beta Tubulin Monoclonal Antibody

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- 宿主: Mouse
- 反应性: Human;Mouse;Rat
- 应用性: WB;IF
Verified Samples |
Verified Samples in WB: Hela, Mouse brain, Rat brain Verified Samples in IF: Hela |
Dilution | WB 1:5000-10000, IF 1:100-200 |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | Synthetic Peptide |
Abbre | β-tubulin |
Synonyms | CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, M(beta)3, M(beta)6, MC1R, Neuron specific beta III Tubulin, Neuron-specific class III beta-tubulin, QccE-11995, QccE-15186, TBB3, TUBB3, TUBB4, Tubb 3, Tubulin, Tubulin beta 3, Tubulin beta 3 chain, Tubulin beta 4, beta 3 tubulin, beta-4 |
Swissprot | |
Calculated MW | 50 kDa |
Observed MW | 55 kDa |
Cellular Localization | Cytoplasm>cytoskeleton. |
Tissue Specificity | Expression is primarily restricted to central and peripheral nervous system. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
Purification Method | Protein A purification |
Research Areas | Cancer, Neuroscience, Signal Transduction, Tags and Cell Markers |
Clone No. | 4A6 |
Conjugation | Unconjugated |
Background | TUBB3,the class III β tubulin or Tuj1,is selectively expressed in testis and neurons of the central and peripheral nervous system. It has been widely used as a marker for neurons. Aberrant expression of TUBB3 has also been found in various tumors of non-neural origin and can be used as a biomarker for cancer aggressiveness and a marker for the tendency to respond poorly to chemotherapy. This antibody is specific to TUBB3 but not cross-react with other tubulin isoforms. |