CASP2 Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: WB
Verified Samples |
Verified Samples in WB: Hela |
Dilution | WB 1:1000-1:5000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein of human CASP2 |
Abbre | CASP2 |
Synonyms | CASP 2, CASP-2, CASP2, Casp2, Caspase 2, Caspase 2 apoptosis related cysteine peptidase, Caspase-2 subunit p12, Caspase2, ICH 1, ICH 1 protease, ICH 1L, ICH1, ICH1 protease, ICH1L, NEDD-2, NEDD2, Neural precursor cell expressed developmentally down-regulated protein 2, PP |
Swissprot | |
Calculated MW | 51 kDa |
Cellular Localization | Cytosol, Mitochondrion, Nucleus, Other locations: cytoplasm, membrane. |
Concentration | 0.4 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology, Metabolism |
Conjugation | Unconjugated |
Background | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
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