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CAV1 Polyclonal Antibody

CAV1 Polyclonal Antibody
  • CAV1 Polyclonal Antibody
  • CAV1 Polyclonal Antibody
  • CAV1 Polyclonal Antibody
  • CAV1 Polyclonal Antibody

Price: ¥3300.00 ¥2220.00 ¥1380.00

Size:
200 μL 120 μL 60 μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB: U87, A549, A431, Mouse heart, Mouse lung, Mouse skin, Rat heart, Rat lung, Rat skin
Verified Samples in IHC: Mouse lung, Rat liver
Dilution
WB 1:500-1:2000, IHC 1:500-1:1000
Clonality
Polyclonal
Isotype
IgG
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Caveolin-1
Abbre
CAV1
Synonyms
22 kD, BSCL3, CAV, CAV1, CGL3, Caveolin 1 caveolae protein 22kDa, Caveolin-1, Caveolin1, LCCNS, MSTP085, OTTHUMP00000025031, PPH3, VIP 21, VIP21, caveolae protein, caveolin 1 alpha isoform, caveolin 1 beta isoform, cell growth-inhibiting protein 32
Swissprot
Calculated MW
20 kDa
Observed MW
20 kDa
Cellular Localization
Golgi apparatus membrane. Cell membrane. Membrane>caveola. Membrane raft. Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae.
Concentration
0.9 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4.
Purification Method
Affinity purification
Research Areas
Cancer, Cardiovascular, Metabolism, Signal Transduction, Tags and Cell Markers
Conjugation
Unconjugated
Background
Caveolin-1 (CAV1),a multifunctional protein,is the main constituent molecule of caveolae and represents a scaffolding molecule for several signaling molecules including epidermal growth factor receptor . Several studies have implicated that a reduced expression of CAV1 was found in cancers including head and neck carcinoma . However,other studies recognize CAV1 as a tumor promoter because CAV1 is overexpressed in various kinds of cancers,especially in oral cancer . Recent study also show that CAV1 is involved in astric Cancer .
Western Blot analysis of various samples using CAV1 Polyclonal Antibody at dilution of 1:800.
Immunohistochemistry analysis of paraffin-embedded mouse lung using CAV1 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded rat liver using CAV1 Polyclonal Antibody at dilution of 1:1000.


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