CAV1 Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB: U87, A549, A431, Mouse heart, Mouse lung, Mouse skin, Rat heart, Rat lung, Rat skin Verified Samples in IHC: Mouse lung, Rat liver |
Dilution | WB 1:500-1:2000, IHC 1:500-1:1000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Caveolin-1 |
Abbre | CAV1 |
Synonyms | 22 kD, BSCL3, CAV, CAV1, CGL3, Caveolin 1 caveolae protein 22kDa, Caveolin-1, Caveolin1, LCCNS, MSTP085, OTTHUMP00000025031, PPH3, VIP 21, VIP21, caveolae protein, caveolin 1 alpha isoform, caveolin 1 beta isoform, cell growth-inhibiting protein 32 |
Swissprot | |
Calculated MW | 20 kDa |
Observed MW | 20 kDa |
Cellular Localization | Golgi apparatus membrane. Cell membrane. Membrane>caveola. Membrane raft. Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. |
Concentration | 0.9 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Metabolism, Signal Transduction, Tags and Cell Markers |
Conjugation | Unconjugated |
Background | Caveolin-1 (CAV1),a multifunctional protein,is the main constituent molecule of caveolae and represents a scaffolding molecule for several signaling molecules including epidermal growth factor receptor . Several studies have implicated that a reduced expression of CAV1 was found in cancers including head and neck carcinoma . However,other studies recognize CAV1 as a tumor promoter because CAV1 is overexpressed in various kinds of cancers,especially in oral cancer . Recent study also show that CAV1 is involved in astric Cancer . |
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E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500 μL , 120 μL , 1 mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 50 mL , 18 mL , 6 mL , 3 mL |
E-IR-R220 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50 Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |