CD163 Polyclonal Antibody
Price:
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB: MH-S, SH-SY5Y, RAW264.7, THP-1, Mouse spleen, RAW264.7, Mouse lung, Mouse lymph nodes, Rat lung |
| Dilution | WB 1:1000-1:2000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein corresponding to Mouse CD163 |
| Abbre | CD163 |
| Synonyms | C163A, CD 163, CD163, CD163 antigen, CD163 molecule, Hemoglobin scavenger receptor, M130, M130 antigen precursor, MM130, Macrophage associated antigen, OTTHUMP00000238617, OTTHUMP00000238618, OTTHUMP00000238619, OTTHUMP00000238620, SCARI1, Scavenger receptor cysteine ri |
| Swissprot | |
| Calculated MW | 125 kDa |
| Observed MW | 145 kDa |
| Cellular Localization | Membrane |
| Concentration | 360 μg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Immunology |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
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