CD34 Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: WB
Verified Samples |
Verified Samples in WB: HUVEC, A549, MCF-7, Mouse lung, Rat liver, Rat spleen |
Dilution | WB 1:500-1:2000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein corresponding to Mouse CD34 |
Abbre | CD34 |
Synonyms | CD34, CD34 antigen, CD34 molecule, Cd34, Cluster designation 34, HPCA1, Hematopoietic progenitor cell antigen CD34, Mucosialin, OTTHUMP00000034733, OTTHUMP00000034734 |
Swissprot | |
Calculated MW | 41 kDa |
Observed MW | 105-120 kDa |
Cellular Localization | Membrane, Cytoplasm. |
Concentration | 0.7 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Developmental Biology, Immunology, Neuroscience, Stem Cells |
Conjugation | Unconjugated |
Background | CD34 is a surface glycophosphoprotein expressed on developmentally early lymphohematopoietic stem and progenitor cells with a molecular weight of about 105-120 kD. It is selectively expressed on the majority of hematopoietic stem/progenitor cells,bone marrow stromal cells,capillary endothelial cells,embryonic fibroblasts,and some nerve tissue. CD34 is a commonly used marker for identifying human hematopoietic stem/progenitor cells and mediates cell adhesion and lymphocyte homing by binding L-selectin and E-selectin ligands. CD34 is also one of the best negative selection markers for characterizing and/or isolating human MSCs from bone marrow and other sources. Along with other positive selection markers (such as CD29,CD44,CD90,CD105 and CD166),negative selection markers (such as CD34 and CD45) are used for MSC identification. |
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