CD68 Monoclonal Antibody

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- 宿主: Mouse
- 反应性: Human;Mouse;Rat
- 应用性: IHC-p;IF
Verified Samples |
Verified Samples in IHC: Human tonsil, Human tonsil Verified Samples in IF: Human lung cancer |
Dilution | IHC 1:100-1:300, IF 1:50-200 |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | Synthetic Peptide |
Abbre | CD68 |
Synonyms | CD 68, CD68, CD68 antigen, CD68 molecule, DKFZp686M18236, Gp110, LAMP4, MACROPHAGE ANTIGEN CD68, Macrophage antigen CD68 (microsialin), Macrosialin, SCARD1, Scavenger receptor class D member 1, gp11 |
Swissprot | |
Cellular Localization | Membrane |
Tissue Specificity | Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
Purification Method | Protein A purification |
Research Areas | Cancer, Immunology |
Clone No. | 2K6 |
Conjugation | Unconjugated |
Background | CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages. |
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