CD74 Polyclonal Antibody

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Price:
Size:
100 μL
25 μL
- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB: Raji Verified Samples in IHC: Human tonsil, Human lung cancer, Mouse spleen, Rat spleen |
Dilution | WB 1:500-1:1000, IHC 1:100-1:300 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant Human HLA class II histocompatibility antigen gamma chain protein |
Abbre | CD74 |
Synonyms | CD 74, CD74, CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, CD74 molecule, CLIP, DHLAG, Gamma chain of class II antigens, class II antigen-associated), class II invariant chain, major histocompatibility complex |
Swissprot | |
Calculated MW | 33,26,18 kDa |
Observed MW | 35 kDa |
Cellular Localization | Cell membrane, Endoplasmic reticulum, Endosome, Golgi apparatus, Lysosome, Membrane. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
Purification Method | Antigen Affinity Purification |
Research Areas | Cancer, Immunology |
Conjugation | Unconjugated |
Background | The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
Western Blot analysis of Raji cell using CD74 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human tonsil using CD74 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human lung cancer using CD74 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Mouse spleen using CD74 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Rat spleen using CD74 Polyclonal Antibody at dilution of 1:200
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E-IR-R220 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50 Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |