CD86 Polyclonal Antibody
Price:
- 宿主： Rabbit
- 反应性： Human
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB: Human lymph gland, Jurkat Verified Samples in IHC: Human gastric cancer |
| Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Fusion protein of human CD86 |
| Abbre | CD86 |
| Synonyms | Activation B7-2 antigen, Activation B7-2 antigen 3, B-lymphocyte activation antigen B7-2, B-lymphocyte activation antigen B7-2 2, B7, B7 2, B7-2, B7.2, B70, B72 antigen, BU63, CD28 antigen ligand 2, CD28 antigen ligand 2 2, CD28LG2, CD86, CD86 antige, CD86 antigen, Cd28l2 |
| Swissprot | |
| Calculated MW | 38 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Membrane. |
| Concentration | 0.5 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol, pH 7.4. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Immunology, Microbiology, Stem Cells |
| Conjugation | Unconjugated |
| Background | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |
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