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CD86 Polyclonal Antibody

CD86 Polyclonal Antibody
  • CD86 Polyclonal Antibody
  • CD86 Polyclonal Antibody

Price: ¥2365.00 ¥1640.00 ¥1010.00 ¥420.00

Size:
200 μL 120 μL 60 μL 20 μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC: Human gastric cancer
Dilution
IHC 1:40-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human CD86
Abbre
CD86
Synonyms
Activation B7-2 antigen, Activation B7-2 antigen 3, B-lymphocyte activation antigen B7-2, B-lymphocyte activation antigen B7-2 2, B7, B7 2, B7-2, B7.2, B70, B72 antigen, BU63, CD28 antigen ligand 2, CD28 antigen ligand 2 2, CD28LG2, CD86, CD86 antige, CD86 antigen, Cd28l2
Swissprot
Cellular Localization
Membrane.
Concentration
0.6 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH 7.4.
Purification Method
Antigen affinity purification
Research Areas
Cancer, Immunology, Microbiology, Stem Cells
Conjugation
Unconjugated
Background
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CD86 Polyclonal Antibody at dilution of 1:55(×200)


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