Claudin 10 Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Human
- 应用性: IHC
Verified Samples |
Verified Samples in IHC: Human colon cancer, Human liver cancer |
Dilution | IHC 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human CLDN10 |
Abbre | CLDN10 |
Synonyms | CPETRL3, OSP-L |
Swissprot | |
Cellular Localization | Plasma Membrane, Other locations: bicellular tight junction, cytoplasm, integral component of membrane. |
Concentration | 0.6 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Signal Transduction |
Conjugation | Unconjugated |
Background | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined. |
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