Connexin 43 Polyclonal Antibody-Elabscience伊莱瑞特【官网】

Connexin 43 Polyclonal Antibody

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货号：E-AB-70097
文献（4）
说明书

说明书

Price: ¥3300.00 ¥2220.00 ¥1380.00

Size:

200 μL 120 μL 60 μL

宿主： Rabbit
反应性： Human;Mouse;Rat
应用性： WB;IHC

Verified Samples	Verified Samples in WB: Hela, HepG2, SW480 Verified Samples in IHC: Mouse heart, Rat heart
Dilution	WB 1:1000-1:2000, IHC 1:300-1:800
Clonality	Polyclonal
Isotype	IgG
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Connexin 43
Abbre	Connexin 43
Synonyms	CXA1, Connexin 43, Connexin-43, Cx 43, Cx43, DFNB38, GJA 1, GJAL, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein, Gap junction protein alpha 1 43kDa, Gap junction protein alpha 1 43kDa (connexin 43), Gap junction protein alpha like, Gja1, ODD, ODDD, ODOD
Swissprot	P17302, P23242, P08050
Calculated MW	43 kDa
Observed MW	43 kDa
Cellular Localization	Cell membrane. Cell junction>gap junction.
Concentration	0.53 mg/mL
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer	PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4.
Purification Method	Affinity purification
Research Areas	Cancer, Cardiovascular, Signal Transduction
Conjugation	Unconjugated
Background	This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.

Western Blot analysis of various samples using Connexin 43 Polyclonal Antibody at dilution of 1:1000.

Immunohistochemistry analysis of paraffin-embedded mouse heart using Connexin 43 Polyclonal Antibody at dilution of 1:300.

Immunohistochemistry analysis of paraffin-embedded rat heart using Connexin 43 Polyclonal Antibody at dilution of 1:300.

A cigarette filter-derived biomimetic cardiac niche for myocardial infarction repair

IF: 18.900

Journal： Bioactive Materials (2024)

DOI：10.1016/j.bioactmat.2024.02.012

PMID：38379697

Reactivity：Rat

Sample Type：heart tissue
Morphological and molecular changes in the Harderian gland of streptozotocin-induced diabetic rats

IF: 2.800

Journal： Journal of Experimental Zoology Part A-Ecological and Integrative Physiology (2023)

DOI：10.1002/jez.2741

PMID：37522474

Reactivity：Rat

Sample Type：Harderian gland (HG)
Molecular and Histological Effects of Glyphosate on Testicular Tissue of the Lizard Podarcis siculus

IF: 6.208

Journal： INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

DOI：10.3390/ijms23094850

PMID：35563240

Reactivity：Lizard

Sample Type：Testes
Vitamin B12 suppresses GADD153, prevents apoptosis and regulates the testicular function in methotrexate treated rat testis

IF: 1.718

Journal： BIOTECHNIC & HISTOCHEMISTRY (2021)

DOI：10.1080/10520295.2021.1962976

PMID：34365888

Reactivity：Rat

Sample Type：testis

E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500 μL , 120 μL , 1 mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50 mL , 18 mL , 6 mL , 3 mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50 Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50 Assays