COX4I1 Monoclonal Antibody
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- 宿主： Mouse
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC-p;IF
| Verified Samples |
Verified Samples in WB: Hela Verified Samples in IHC: Rat kidney Verified Samples in IF: Mouse kidney |
| Dilution | WB 1:1000-3000, IHC 1:50-300, IF 1:100-1:300 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Recombinant Protein |
| Abbre | COX IV |
| Synonyms | AL024441, COX 4, COX IV, COX IV 1, COX IV-1, COX41, COX4B, COX4I1, COX4I2, COX4L2, COXIV, Cox4, Cox4a, Cytochrome C Oxidas, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit 4 isoform 1, Cytochrome c oxidase subunit 4 isoform 1 mitochondrial, mitochondrial |
| Swissprot | |
| Calculated MW | 20 kDa |
| Observed MW | 15 kDa |
| Cellular Localization | Mitochondrion inner membrane. |
| Tissue Specificity | Ubiquitous |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Metabolism, Signal Transduction, Tags and Cell Markers |
| Clone No. | 2D4 |
| Conjugation | Unconjugated |
| Background | Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. |
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Inhibition mechanism of naphthylphenylamine derivatives acting on the CDC25B dual phosphatase and analysis of the molecular processes involved in the high cytotoxicity exerted by one selected derivative in melanoma cells
IF: 4.673Journal： JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2020)PMID：32990107Reactivity：MouseSample Type：Antibody -
Mitochondrial amidoxime-reducing component 2 (MARC2) has a significant role in N-reductive activity and energy metabolism
IF: 4.106 -
Stretching magnitude–dependent inactivation of AKT by ROS led to enhanced p53 mitochondrial translocation and myoblast apoptosis
IF: 3.905Journal： MOLECULAR BIOLOGY OF THE CELL (2019)PMID：30865562Reactivity：RatSample Type：Tissue homogenate
