E-Cadherin Polyclonal Antibody-Elabscience伊莱瑞特【官网】

E-Cadherin Polyclonal Antibody

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货号：D-AB-10198L
文献（4）
说明书

说明书

Price: ¥2100.00 ¥800.00

Size:

100 μL 25 μL

宿主： Rabbit
反应性： Human;Mouse;Rat
应用性： WB;IHC

Verified Samples	Verified Samples in WB: Mouse spleen, Rat brain Verified Samples in IHC: Human carcinoma of Colon, Human breast cancer, Human Placenta, Human ovarian cancer
Dilution	WB 1:500-1:1000, IHC 1:100-1:200
Clonality	Polyclonal
Isotype	IgG
Immunogen	Recombinant Human CDH1 protein expressed by E.coli
Abbre	E-Cadherin
Synonyms	Arc 1, CADH1, CAM 120/80, CD 324, CD324, CD324 antigen, CDHE, Cadherin 1, Cadherin1, E-Cad/CTF3, E-cadherin, ECAD, Epithelial cadherin, LCAM, Liver cell adhesion molecule, UVO, Uvomorulin, cadherin 1 type 1 E-cadherin, cdh1, epithelial calcium dependant adhesion protein
Swissprot	P12830
Calculated MW	97 kDa
Observed MW	135 kDa
Concentration	1 mg/mL
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer	PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Purification Method	Antigen Affinity Purification
Research Areas	Cancer, Developmental Biology, Signal Transduction
Conjugation	Unconjugated
Background	This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats,a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric,breast,colorectal,thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation,invasion,and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.

Western blot with E-Cadherin Polyclonal antibody at dilution of 1:1000.lane 1:Mouse spleen,lane 2:Rat brain

Immunohistochemistry of paraffin-embedded Human carcinoma of Colon using E-Cadherin Polyclonal Antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded Human breast cancer using E-Cadherin Polyclonal Antibody at dilution of 1:200

Immunohistochemistry of paraffin-embedded Human Placenta using E-Cadherin Polyclonal Antibody at dilution of 1:100(Elabscience Product)

Immunohistochemistry of paraffin-embedded Human ovarian cancer using E-Cadherin Polyclonal Antibody at dilution of 1:200

A potent Bioorganic azapodophyllotoxin derivative Suppresses tumor Progression in Triple negative breast Cancer: An Insight into its Inhibitory effect on tubulin polymerization and Disruptive effect on microtubule assembly

IF: 4.500

Journal： BIOORGANIC CHEMISTRY (2024)

DOI：10.1016/j.bioorg.2024.107839

Reactivity：Human
Expression of Markers Associated with Epithelial—Mesenchymal Transition and Extracellular Matrix Degradation in Human Uveal Melanoma

IF: 0.900

Journal： BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2024)

DOI：10.1007/s10517-024-06266-x

Reactivity：Human

Sample Type：choroid tissue without tumor
Hypermethylation of the GRHL2 promoter region is associated with ovarian endometriosis

IF: 3.923

Journal： REPRODUCTION (2022)

DOI：10.1530/REP-21-0383

Reactivity：Human
Anti-inflammatory effect of epidermal growth factor conjugated silk fibroin immobilized polyurethane ameliorates diabetic burn wound healing

IF: 4.784

Journal： INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

DOI：10.1016/j.ijbiomac.2019.09.219

PMID：31647938

Reactivity：Rat

Sample Type：Serum,Tissue homogenate

E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500 μL , 120 μL , 1 mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50 mL , 18 mL , 6 mL , 3 mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50 Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50 Assays