EDG3 Polyclonal Antibody

Price:
- 宿主: Rabbit
- 反应性: Human;Mouse
- 应用性: WB
Verified Samples |
Verified Samples in WB: PC-3 |
Dilution | WB 1:500-1:2000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human S1PR3 |
Abbre | S1PR3 |
Synonyms | EDG 3, EDG3, Endothelial differentiation G protein coupled receptor 3, Endothelial differentiation G-protein coupled receptor 3, Endothelial differentiation gene 3, Endothelial differentiation sphingolipid G protein coupled receptor 3, FLJ37523, FLJ93220, G prote |
Swissprot | |
Calculated MW | 42 kDa |
Cellular Localization | Cell membrane. |
Concentration | 0.3 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Signal Transduction |
Conjugation | Unconjugated |
Background | This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. |
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