FN1 Monoclonal Antibody
Price:
- 宿主： Mouse
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC-p;IF
| Verified Samples |
Verified Samples in WB: Hela Verified Samples in IHC: Rat liver Verified Samples in IF: Human appendix |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:300, IF 1:100-1:300 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Synthetic Peptide |
| Abbre | Fibronectin |
| Synonyms | CIG, Cold insoluble globulin, Cold-insoluble globulin, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED B, FINC, FN, FN1, FNZ, Fibronectin 1, GFND, GFND2, LETS, MSF, Migration stimulating factor, Ugl-Y3 |
| Swissprot | |
| Calculated MW | 263 kDa |
| Observed MW | 285 kDa |
| Cellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Cardiovascular, Developmental Biology, Signal Transduction, Stem Cells |
| Clone No. | 9A5 |
| Conjugation | Unconjugated |
| Background | This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. |
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