Galectin 3 Monoclonal Antibody

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- 宿主: Mouse
- 反应性: Human
- 应用性: WB;IHC-p;IF
Verified Samples |
Verified Samples in WB: Hela Verified Samples in IHC: Human thyroid Verified Samples in IF: Human lung cancer |
Dilution | WB 1:1000-1:3000, IHC 1:100-1:300, IF 1:100-200 |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | Synthetic Peptide |
Abbre | Galectin-3 |
Synonyms | 35 kDa lectin, CBP 35, CBP35, Carbohydrate binding protein 35, Carbohydrate-binding protein 35, GAL3, GALBP, GALIG, GBP, Gal-3, Galactose-specific lectin 3, Galactoside-binding protein, Galectin 3 internal gene, Galectin-3, Galectin3, IgE binding protein, IgE-bi, included |
Swissprot | |
Calculated MW | 26 kDa |
Observed MW | 26 kDa |
Cellular Localization | Nucleus. Cytoplasmic in adenomas and carcinomas. May be secreted by a non-classical secretory pathway and associate with the cell surface. |
Tissue Specificity | A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
Purification Method | Protein A purification |
Research Areas | Cancer, Cell Biology, Neuroscience |
Clone No. | 1A2 |
Conjugation | Unconjugated |
Background | Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. |
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Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer
IF: 11.400Journal: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2024)