Histone H3 Monoclonal Antibody-Elabscience伊莱瑞特【官网】

Histone H3 Monoclonal Antibody

一键复制产品信息

货号：E-AB-22003
文献（3）
说明书

说明书

Price: ¥2310.00 ¥1420.00 ¥580.00

Size:

120 μL 60 μL 20 μL

宿主： Mouse
反应性： Human;Mouse;Rat;Yeast
应用性： WB;IF

Verified Samples	Verified Samples in WB: Hela, RAW264.7, Mouse brain, Rat brain Verified Samples in IHC: Human uterus Verified Samples in IF: Rat liver
Dilution	WB 1:500-1:2000, IHC 1:50-300, IF 1:100-500, IP 1:100-1:300
Clonality	Monoclonal
Isotype	IgG
Immunogen	Recombinant Protein
Abbre	Histone H3
Synonyms	H3FA, H3FB, H3FC, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, Histone H3.1, Histone H3/, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f
Swissprot	P68431, Q71DI3, P84243
Calculated MW	15 kDa
Observed MW	15 kDa
Cellular Localization	Extracellular region or secreted, extracellular exosome, extracellular region, Nucleus, nuclear chromosome, nuclear chromosome, telomeric region, nuclear nucleosome, nucleoplasm, nucleus, Other locations: nucleosome, protein complex.
Concentration	1 mg/mL
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4.
Purification Method	Protein A purification
Research Areas	Cancer, Epigenetics and Nuclear Signaling
Clone No.	5B1
Conjugation	Unconjugated
Background	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Western Blot analysis of 1) Hela, 2) Raw264.7, 3) Mouse brain, 4) Rat brain using Histone H3 Monoclonal Antibody at dilution of 1:5000.

Immunofluorescence analysis of Rat liver tissue using Histone H3 Monoclonal Antibody at dilution of 1:200.

Protein UFMylation regulates early events during ribosomal DNA-damage response

IF: 7.500

Journal： Cell Reports (2024)

DOI：10.1016/j.celrep.2024.114738

Reactivity：Human
A CRISPR/Cas9 screen in embryonic stem cells reveals that Mdm2 regulates totipotency exit

IF: 5.200

Journal： Communications Biology (2024)

DOI：10.1038/s42003-024-06507-9

Reactivity：Mouse
Sex Differences and Cytokine Profiles among Patients Hospitalized for COVID-19 and during Their Recovery: The Predominance of Adhesion Molecules in Females and Oxidative Stress in Males

IF: 7.800

Journal： Vaccines (2023)

DOI：10.3390/vaccines11101560

PMID：37896963

Reactivity：Human

E-AB-1001	Goat Anti-Mouse IgG(H+L)(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1011	Goat Anti-Mouse IgG(H+L)(Cyanine3 conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1015	Goat Anti-Mouse IgG(H+L)(FITC conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1024	Goat Anti-Mouse IgG(H+L)(Biotin conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1059	Goat Anti-Mouse IgG(H+L)(Elab Fluor® 594 conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1076	Goat Anti-Mouse IgG(H+L)(Elab Fluor® 647 conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1196	HRP-Goat Anti-Mouse IgG(H+L) preadsorbed	500 μL , 120 μL , 1 mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50 mL , 18 mL , 6 mL , 3 mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50 Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50 Assays