HLA-G Polyclonal Antibody
Price:
- 宿主： Rabbit
- 反应性： Human
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC: Human esophagus cancer |
| Dilution | IHC 1:50-1:300 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human HLA-G |
| Abbre | HLA-G |
| Synonyms | B2 microglobulin, DADB-15K14.8, HLA 6.0, HLA G, HLA G antigen, HLA G histocompatibility antigen class I G, HLA G3, HLA class I histocompatibility antigen, HLA class I histocompatibility antigen alpha chain G, HLA class I molecule, HLA-G, HLA-G histoco, alpha chain G |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 1.26 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol, pH 7.4. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Immunology |
| Conjugation | Unconjugated |
| Background | Human major histocompatibility complex (MHC) antigens,also referred to as human leukocyte antigens (HLA),are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface,where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance. |
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The modeling of human implantation and early placentation: achievements and perspectives
IF: 14.800 -
HLA-G Expression/Secretion and T-Cell Cytotoxicity in Missed Abortion in Comparison to Normal Pregnancy
IF: 5.600Journal： INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2024)PMID：38473890Reactivity：HumanSample Type：gestational tissue -
Functional HLA-C expressing trophoblast spheroids as a model to study placental–maternal immune interactions during human implantation
IF: 4.996
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| E-IR-R304A | Western Blot Detection Kit | 50 Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |
