IDO2 Polyclonal Antibody
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- 宿主： Rabbit
- 反应性： Human
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB: Human fetal brain, Human kidney Verified Samples in IHC: Human brain |
| Dilution | WB 1:500-1:2000, IHC 1:30-1:150 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Full length fusion protein |
| Abbre | IDO2 |
| Synonyms | 3 dioxygenase 2, 3 dioxygenase l, 3 dioxygenase like 1 protein, 3 dioxygenase like protein 1, 3-dioxygenase 2, 3-dioxygenase-like protein 1, EC 1.13.11., I23O2, IDO 2, IDO-2, INDOL 1, Ido2, Indoleamine 2, Indoleamine pyrrole 2 |
| Swissprot | |
| Calculated MW | 45 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytosol, Other locations: cytoplasm. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol, pH 7.4. |
| Purification Method | Antigen affinity purification |
| Research Areas | Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Background | INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1. |
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500 μL , 120 μL , 1 mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 50 mL , 18 mL , 6 mL , 3 mL |
| E-IR-R220 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50 Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |
