IL6 Polyclonal Antibody
Price:
- 宿主： Rabbit
- 反应性： Human
- 应用性： WB
| Verified Samples |
Verified Samples in WB: HepG2, Hela, A549 |
| Dilution | WB 1:500-1:2000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human IL6 |
| Abbre | IL6 |
| Synonyms | IFNB, Interleukin HP, Interferon Beta, B-Cell Stimulatory Factor, IFN-Beta, B-cell hybridoma growth factor, B-Cell Stimulatory Factor 2, BSF2, BSF-2, CDF, CTL Differentiation Factor, HGF, HSF, Hybridoma Growth Factor, IFN-Beta-2, IL-6, Interferon Beta-2, Interleukin 6, Interleukin HP-1, Interleukin-6, IL6, IFNB2, B cell differentiation factor, B cell stimulatory factor 2, BSF 2, Hepatocyte stimulatory factor, Hybridoma growth factor Interferon beta-2, IL 6, Interferon beta 2, Interleukin 6 (interferon beta 2), Interleukin BSF 2, Interleukin-6, IL-6, B-cell hybridoma growth factor, Interleukin HP-1 |
| Swissprot | |
| Calculated MW | 24 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Secreted. |
| Concentration | 1.1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol, pH 7.4. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Metabolism, Immunology, Neuroscience |
| Conjugation | Unconjugated |
| Background | Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells,T-cells,hepatocytes,hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine,a cytokine produced from muscle,and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally,IL-6 is involved in hematopoiesis,bone metabolism,and cancer progression,and has been defined an essential role in directing transition from innate to acquired immunity. |
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