MICU1 Monoclonal Antibody-Elabscience伊莱瑞特【官网】

MICU1 Monoclonal Antibody

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货号：E-AB-22114
说明书

说明书

Price: ¥2310.00 ¥1420.00 ¥580.00

Size:

120 μL 60 μL 20 μL

宿主： Mouse
反应性： Human;Mouse;Rat
应用性： WB;IHC-p;IF

Verified Samples	Verified Samples in WB: MCF-7, Mouse brain, Rat brain Verified Samples in IHC: Mouse testis Verified Samples in IF: Human appendix
Dilution	WB 1:500-1:2000, IHC 1:100-1:200, IF 1:100-1:300
Clonality	Monoclonal
Isotype	IgG
Immunogen	Recombinant Protein
Abbre	MICU1
Synonyms	Allergen Hom s 4, Atopy-related autoantigen CALC, CALC, Calcium uptake protein 1, Calcium-binding atopy-relate, ara CALC, atopy related autoantigen, atopy related autoantigen CALC, calcium binding atopy related autoantigen 1, calcium uptake protein 1, mitochondrial
Swissprot	Q9BPX6
Observed MW	55 kDa
Cellular Localization	Mitochondrion inner membrane.
Tissue Specificity	Expressed in epithelial cell line. Strongly expressed in epidermal keratinocytes and dermal endothelial cells.
Concentration	1 mg/mL
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4.
Purification Method	Protein A purification
Research Areas	Cancer, Metabolism, Immunology, Signal Transduction
Clone No.	4E7
Conjugation	Unconjugated
Background	This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.

Western Blot analysis of 1) MCF7, 2) Mouse brain, 3) Rat brain with MICU1 Monoclonal Antibody.

Immunohistochemistry of paraffin-embedded Mouse testis tissue using MICU1 Monoclonal Antibody at dilution of 1:200.

Immunofluorescence analysis of Human appendix tissue using MICU1 Monoclonal Antibody at dilution of 1:200.

E-AB-1001	Goat Anti-Mouse IgG(H+L)(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1011	Goat Anti-Mouse IgG(H+L)(Cyanine3 conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1015	Goat Anti-Mouse IgG(H+L)(FITC conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1024	Goat Anti-Mouse IgG(H+L)(Biotin conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1059	Goat Anti-Mouse IgG(H+L)(Elab Fluor® 594 conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1076	Goat Anti-Mouse IgG(H+L)(Elab Fluor® 647 conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1196	HRP-Goat Anti-Mouse IgG(H+L) preadsorbed	500 μL , 120 μL , 1 mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50 mL , 18 mL , 6 mL , 3 mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50 Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50 Assays