N-cadherin Polyclonal Antibody
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- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB: HCT116, HUVEC, Hela, Rat liver, Rat kidney, Rat brain, Mouse liver, Mouse kidney, Mouse brain Verified Samples in IHC: Human liver, Mouse liver, Rat liver |
| Dilution | WB 1:500-1:2000, IHC 1:300-1:800 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse N-cadherin |
| Abbre | N-cadherin |
| Synonyms | CADH2, CD325, CD325 antigen, CDH2, CDHN, CDw325, CDw325 an, Cadherin 2, Cadherin 2 N cadherin neuronal, Cadherin 2 type 1, Cadherin 2 type 1 N cadherin neuronal, Cadherin-2, Cadherin2, Calcium dependent adhesion protein neuronal, N-cadherin (neuronal), type 1 |
| Swissprot | |
| Calculated MW | 100/120 /140 kDa |
| Observed MW | 120 kDa |
| Cellular Localization | Cell junction, Cell membrane, Membrane. |
| Concentration | 200 μg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Background | Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin),also known as CDH2 (cadherin 2),is a classical member of the cadherin superfamily which also include E-,P-,R-,and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons,endothelial cells and cardiac myocytes . N-cadherin has functions in early brain morphogenesis,synaptogenesis and synaptic plasticity . |
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