Phospho-ERK 1/2 (Thr202/Tyr204) Polyclonal Antibody
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- 宿主： Rabbit
- 反应性： Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB: Hela, HUVEC, NIH/3T3, Mouse lung, Mouse kidney, Rat lung, Rat kidney |
| Dilution | WB 1:500-1:2000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse ERK2 |
| Abbre | ERK1/2 |
| Synonyms | ERK-1, ERK1, ERT2, Extracellular signal-regulated kinase 1, Insulin-stimulated MAP2 kinase, MAP kinase 3, MAP kinase isoform p44, MAPK 3, MAPK3, Microtubule-associated protein 2 kinase, Mitogen-activated protein kinase 3, PRKM3, p44-MAPK |
| Swissprot | |
| Calculated MW | 42/44 kDa |
| Observed MW | 42 /44 kDa |
| Cellular Localization | Cytoplasm, Cytoskeleton, Membrane, Nucleus. |
| Concentration | 1.1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
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