PRDX1 Monoclonal Antibody

Price:
- 宿主: Mouse
- 反应性: Human;Mouse;Rat
- 应用性: WB;IHC-p;IF
Verified Samples |
Verified Samples in WB: MCF-7, Rat kidney, Mouse brain Verified Samples in IHC: Human uterus cancer Verified Samples in IF: Hela |
Dilution | WB 1:500-1:3000, IHC 1:50-1:300, IF 1:100-1:200 |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | Recombinant Protein |
Abbre | Peroxiredoxin 1 |
Synonyms | Heme binding 23 kDa protein, MSP23, NKEF A, NKEF-A, NKEFA, Natural killer cell-enhancing factor A, OSF3, Osteoblast specific factor 3, PAG, PAGB, PRDX1, PRX1, Paga, Peroxiredoxin-1, Proliferation associated gene A, Proliferation-associated gene protein, PrxI, TDPX2 |
Swissprot | |
Observed MW | 21 kDa |
Cellular Localization | Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4. |
Purification Method | Protein A purification |
Research Areas | Cancer, Cell Biology, Cardiovascular, Metabolism |
Clone No. | 2J5 |
Conjugation | Unconjugated |
Background | Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. |