Recombinant GSDMD Monoclonal Antibody
Price:
Size:
100 μL
50 μL
- 宿主： Rabbit
- 反应性： Human
- 应用性： WB
| Verified Samples |
Verified Samples in WB: Jurkat |
| Dilution | WB 1:500-1:1000 |
| Clonality | Rabbit Monoclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein of human GSDMD |
| Abbre | GSDMD |
| Synonyms | DF5L, DFNA5L, FKSG10, GSDMD, GSDMDC1 |
| Swissprot | |
| Calculated MW | 53 kDa |
| Observed MW | 53 kDa |
| Cellular Localization | Cytosol, NLRP3 inflammasome complex, Extracellular region or secreted, extracellular region, extracellular space, Nucleus, nucleoplasm, Plasma Membrane, Other locations: ficolin-1-rich granule lumen, specific granule lumen, tertiary granule lumen. |
| Concentration | 300 μg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. |
| Purification Method | Affinity Purified |
| Research Areas | Cell Biology |
| Clone No. | R06-5C5 |
| Conjugation | Unconjugated |
| Background | GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently,GSDMD is identified as a new component of inflammasomes,and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. |
Western blot detection of GSDMD in Jurkat cell lysates using GSDMD Rabbit mAb(1:500 diluted).Predicted band size:53kDa.Observed band size:53kDa.
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500 μL , 120 μL , 1 mL |
| E-IR-R304A | Western Blot Detection Kit | 50 Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |
