TLR3 Polyclonal Antibody
Price:
- 宿主： Rabbit
- 反应性： Human;Mouse
- 应用性： WB
| Verified Samples |
Verified Samples in WB: Raji, K562 |
| Dilution | WB 1:500-1:2000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein of human TLR3 |
| Abbre | TLR3 |
| Synonyms | CD283, CD283 antigen, IIAE2, TLR 3, TLR3, Tlr3, Toll Like Receptor 3, Toll-like receptor 3 |
| Swissprot | |
| Calculated MW | 104 kDa |
| Cellular Localization | Endoplasmic reticulum membrane. Endosome membrane. |
| Concentration | 0.3 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, pH 7.4. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology, Microbiology, Signal Transduction |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity.TLRs are highly conserved from Drosophila to humans and share structural and functional similarities.They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.The various TLRs exhibit different patterns of expression.This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes.It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons.It may thus play a role in host defense against viruses.Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. |
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| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500 μL , 120 μL , 1 mL |
| E-IR-R304A | Western Blot Detection Kit | 50 Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |
