TRAIL Polyclonal Antibody
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- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB: A549, Mouse spleen, Mouse lung, Mouse prostate, Rat spleen, Rat lung, Rat prostate |
| Dilution | WB 1:500-1:2000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Trail |
| Abbre | TRAIL |
| Synonyms | APO 2L, APO2L, Apo 2 ligand, Apo-2 ligand, Apo-2L, CD253, CD253 antigen, Chemokine tumor necrosis factor ligand superfamily member 10, Protein TRAIL, TL2, TNF Related Apoptosis Inducing Ligand, TNF related apoptosis inducing ligand TRAIL, TNF-related apoptosis-induci |
| Swissprot | |
| Calculated MW | 33 kDa |
| Observed MW | 33 kDa |
| Cellular Localization | Membrane. |
| Concentration | 0.94 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Cardiovascular |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG.The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis.The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3.Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500 μL , 120 μL , 1 mL |
| E-IR-R304A | Western Blot Detection Kit | 50 Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |
