Vimentin Polyclonal Antibody-Elabscience伊莱瑞特【官网】

Vimentin Polyclonal Antibody

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货号：E-AB-70081
文献（9）
说明书

说明书

Price: ¥3300.00 ¥2220.00 ¥1380.00

Size:

200 μL 120 μL 60 μL

宿主： Rabbit
反应性： Human;Mouse;Rat
应用性： WB;IHC

Verified Samples	Verified Samples in WB: Hela, HepG2, SW480, B16, PC12, Mouse lung Verified Samples in IHC: Human lung cancer, Human colon, Human liver cancer, Human kidney
Dilution	WB 1:500-1:2000, IHC 1:200-1:800
Clonality	Polyclonal
Isotype	IgG
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse vimentin
Abbre	Vimentin
Synonyms	CTRCT30, Epididymis luminal protein 113, FLJ36605, HEL113, VIM, VIME, Vimentin
Swissprot	P08670, P20152, P31000
Calculated MW	57 kDa
Observed MW	57 kDa
Cellular Localization	Cytoplasm
Concentration	1.1 mg/mL
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer	PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4.
Purification Method	Affinity purification
Research Areas	Cancer, Developmental Biology, Neuroscience, Signal Transduction, Stem Cells
Conjugation	Unconjugated
Background	Vimentin,also named as VIM,belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells,especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha (TNFA; 191160) and inhibited by the antiinflammatory cytokine IL10 (124092),suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein,55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.

Western Blot analysis of various samples using Vimentin Polyclonal Antibody at dilution of 1:1000.

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Vimentin Polyclonal Antibody at dilution of 1:300.

Immunohistochemistry analysis of paraffin-embedded Human colon using Vimentin Polyclonal Antibody at dilution of 1:300.

Immunohistochemistry analysis of paraffin-embedded Human liver cancer using Vimentin Polyclonal Antibody at dilution of 1:300.

Immunohistochemistry analysis of paraffin-embedded Human Kidney using Vimentin Polyclonal Antibody(Elabscience Product Detected by Lifespan).

A multifunctional silk-hyaluronic acid self-healing hydrogel laden with alternatively activated macrophage-derived exosomes reshape microenvironment of diabetic wound and accelerate healing

IF: 7.700

Journal： INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2024)

DOI：10.1016/j.ijbiomac.2024.132384

Reactivity：Rat
Simultaneous regulation of AGE/RAGE signaling and MMP-9 expression by an immunomodulating hydrogel accelerates healing in diabetic wounds

IF: 5.500

Journal： Biomaterials Advances (2024)

DOI：10.1016/j.bioadv.2024.213937

Reactivity：Rat

Sample Type：wound bed tissue
Expression of Markers Associated with Epithelial—Mesenchymal Transition and Extracellular Matrix Degradation in Human Uveal Melanoma

IF: 0.900

Journal： BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2024)

DOI：10.1007/s10517-024-06266-x

Reactivity：Human

Sample Type：choroid tissue without tumor
Palmitic Acid Inhibits the Growth and Metastasis of Gastric Cancer by Blocking the STAT3 Signaling Pathway

IF: 5.200

Journal： Cancers (2023)

DOI：10.3390/cancers15020388

PMID：36672337

Reactivity：Human
The Effect of Hydroxytyrosol in Type II Epithelial-Mesenchymal Transition in Human Skin Wound Healing

IF: 4.600

Journal： MOLECULES (2023)

DOI：10.3390/molecules28062652

PMID：36985625

Reactivity：Human
Quinacrine inhibits cMET-mediated metastasis and angiogenesis in breast cancer stem cells

IF: 4.100

Journal： Journal of Cell Communication and Signaling (2023)

DOI：10.1007/s12079-023-00756-9

PMID：37162635

Reactivity：Human
Hypermethylation of the GRHL2 promoter region is associated with ovarian endometriosis

IF: 3.923

Journal： REPRODUCTION (2022)

DOI：10.1530/REP-21-0383

Reactivity：Human
LncRNA PVT1 Promotes Cell Proliferation, Invasion, and Migration and Inhibits Cell Apoptosis by Phosphorylating YAP

IF: 2.605

Journal： Canadian Journal of Gastroenterology and Hepatology (2022)

DOI：10.1155/2022/5332129

PMID：35664988

Reactivity：Human
Silenced SNHG1 Inhibited Epithelial-Mesenchymal Transition and Inflammatory Response of ARPE-19 Cells Induced by High Glucose

IF: 6.922

Journal： Journal of Inflammation Research (2021)

DOI：10.2147/JIR.S299010

PMID：33907437

Reactivity：Human

E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500 μL , 120 μL , 1 mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50 mL , 18 mL , 6 mL , 3 mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50 Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50 Assays