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XRCC4 Monoclonal Antibody

XRCC4 Monoclonal Antibody
  • XRCC4 Monoclonal Antibody
  • XRCC4 Monoclonal Antibody
  • XRCC4 Monoclonal Antibody
  • XRCC4 Monoclonal Antibody

Price: ¥2310.00 ¥1420.00 ¥580.00

Size:
120 μL 60 μL 20 μL
  • 宿主: Mouse
  • 反应性: Human
  • 应用性: WB;IHC-p;IF;IP
Verified Samples
Verified Samples in WB: Hela, 293T
Verified Samples in IHC: Human breast cancer
Verified Samples in IF: Human liver cancer
Dilution
WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
Clonality
Monoclonal
Isotype
IgG
Immunogen
Synthetic Peptide
Abbre
XRCC4
Synonyms
DNA double strand break repair and V(D)J recombination protein XRCC4, DNA repair protein XRCC4, SSMED, X ray repair complementing defective repair in Chinese hamster cells 4, X ray repair cross complementing 4, X ray repair cross complementing protein 4, X-ray
Swissprot
Calculated MW
38 kDa
Observed MW
38 kDa
Cellular Localization
Nucleus.
Tissue Specificity
Widely expressed
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4.
Purification Method
Protein A purification
Research Areas
Cancer, Epigenetics and Nuclear Signaling
Clone No.
8K2
Conjugation
Unconjugated
Background
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Western Blot analysis of 1) Hela, 2) 293T cells using XRCC4 Monoclonal Antibody at dilution of 1:3000.
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using XRCC4 Monoclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Human liver cancer tissue using XRCC4 Monoclonal Antibody at dilution of 1:200.
E-AB-1001 Goat Anti-Mouse IgG(H+L)(peroxidase/HRP conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1011 Goat Anti-Mouse IgG(H+L)(Cyanine3 conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1015 Goat Anti-Mouse IgG(H+L)(FITC conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1024 Goat Anti-Mouse IgG(H+L)(Biotin conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1043 Streptavidin(peroxidase/HRP conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1059 Goat Anti-Mouse IgG(H+L)(Elab Fluor® 594 conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1076 Goat Anti-Mouse IgG(H+L)(Elab Fluor® 647 conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1196 HRP-Goat Anti-Mouse IgG(H+L) preadsorbed 500 μL , 120 μL , 1 mL
E-IR-R217 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) 50 mL , 18 mL , 6 mL , 3 mL
E-IR-R220 Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) 10mL , 3mL
E-IR-R221 Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) 10mL , 3mL
E-IR-R304A Western Blot Detection Kit 50 Assays
E-IR-R304B High Accuracy and Absorbability Western Blot Detection Kit 50 Assays


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